Harvard University research: 40% of diseases are caused by genetics, and 25% of diseases are caused by the environment

According to a recent report by the British “Daily Mail”, scientists at Harvard University in the United States conducted a 24-year follow-up survey of 45 million Americans to study which diseases are caused by genes and which diseases are more susceptible to environmental influences. It is by far the largest study of its kind.

According to the latest study published in the journal Nature Genetics, 40% of the 560 diseases investigated were genetically induced, and at least 25% of the diseases were caused by the environment. Knowing problems is most closely related to genetics, while eye diseases are most affected by the environment.

In general, most diseases are the result of interactions between innate genes and acquired environments. The environment can change the way genes are sorted, and genes can affect the body’s response to the environment. And everyone’s genes are unique, and the environment is unique and constantly changing. The interaction between genes and the environment also varies from disease to disease.

Researchers at Harvard University collected data on 45 million people through insurance information databases, comparing genetic data, disease diagnosis, and biomedical statistics such as height and weight with the genetic code of the subject to infer socioeconomic status. The impact of the environment on the disease.

The data of 56,000 pairs of twins in the subjects provided some of the most critical information for the study. Especially identical twins can provide a rare opportunity for geneticists to observe changes in the same genes in different environments.

Researchers at Harvard University have found that more than 6,000 cases of hereditary diseases are genetic defects caused by the deletion of certain gene sequences. Nearly 40% of the diseases studied, including musculoskeletal, cognitive, eye, respiratory and reproductive diseases, are caused by heredity.

The research team has studied 560 diseases and found that at least 25% of the diseases are caused by the environment. Among them, 27 of the 42 eye diseases are caused by environmental factors; in addition to eye diseases, respiratory diseases are the diseases most closely related to environmental factors; reproductive disorders are least affected by the environment. In cognitive diseases, four-fifths are genetic; while connective tissue diseases, such as rheumatoid arthritis, are least affected by genes.

Genetic factors may even change environmental factors (socioeconomic status), further changing the risk of disease. Socioeconomic status affects 145 different diseases, of which obesity is the most susceptible to disease. In general, environmental factors are less predictive of disease than genetic factors.

However, environmental factors have a great impact on the risk of disease. The study shows that the results of the study indicate that climate change has and will continue to have a major impact on people’s health. Temperature changes have changed the risk of 117 different diseases, even higher than the risk of air pollution.

Dr. Patel, the head of the study, said: “The core issue of our research is ‘innate and acquired relationships. The value of this large-scale analysis is that it will reveal the effects of genes relative to the common environment in many diseases. Will help the disease to be better prevented and treated.”