Gathering with friends, pushing a cup and changing a cup, remembering that it is time to take medicine, and picking up the drink in your hand is about to give it away. As everyone knows, most drugs do not like to mix and match with beverages. In addition to not drinking alcohol while taking medicine, dairy products, fruit and vegetable juices, etc. may interfere with the medicine. Specifically, it is mainly divided into the following situations.
Drugs to avoid milk: theophylline, Lol, isoniazid, tetracyclines, antidiarrheals, etc. Milk is high in protein, which can affect theophylline bioavailability. Milk can slow down gastric emptying, change the first-pass effect of drugs in the liver, and affect the efficacy of propranolol and metoprolol. Taking isoniazid and milk together will cause histamine to accumulate in the body, resulting in symptoms such as chills, fever, headache, itchy face or scalp, and rapid heartbeat. Tetracyclines have a high affinity with calcium, and will form complexes with milk, which are difficult to absorb in the intestine. Do not drink milk when taking antidiarrheal medicine. Milk will not only reduce the efficacy of the medicine, but its lactose content may also aggravate diarrhea symptoms. Taking zinc, bismuth preparations and bisphosphonates together with milk will produce precipitation and reduce the curative effect.
Drugs that avoid fruit and vegetable juices: antibiotics, non-steroidal anti-inflammatory drugs, etc. Active ingredients such as furocoumarin and naringenin contained in grapefruit (grapefruit) can inhibit lipid-lowering drugs such as simvastatin, antihypertensive drugs such as felodipine, cyclosporine, buspirone, and kama The metabolism of various drugs such as xipine, midazolam, cisapride, imipramine, warfarin, and theophylline increases the blood drug concentration in the body. In addition, fruit juice is mostly acidic, which can accelerate the decomposition of antibiotics and affect the curative effect; it may also aggravate the stimulation of non-steroidal anti-inflammatory drugs such as aspirin on the gastric mucosa. Potassium oxalate is contained in spinach and other vegetable juices. Taking it together with calcium supplements will not only precipitate calcium ions, hinder the body’s absorption of calcium, but also easily form calcium oxalate stones.
Drugs that avoid tea and coffee: antipyretics, berberine, and drugs containing metal ions. Avoid drinking coffee while taking ibuprofen, the latter will aggravate ibuprofen’s irritation to the gastric mucosa. Avoid drinking tea when taking berberine, drugs containing metal ions, such as iron supplements, calcium supplements, pectin bismuth preparations, and aluminum-containing drugs, because the tannins in the tea will be decomposed into tannins after entering the body, making biological Alkali, metal ion precipitation, reduce efficacy.
Drugs that should not be drunk cold: some Chinese patent medicines. When taking cold-dispelling Chinese patent medicines such as Fuzi Lizhong Pills and Wenzhong Yangwei Pills, it is not advisable to take cold drinks, such as watermelon juice, cold drinks, etc. at the same time.
Avoid hot drinks: multi-enzyme tablets, probiotic preparations. The active protein in the enzyme will coagulate and denature after being heated, and lose its digestion function, and the probiotics may be inactivated by heating, affecting the curative effect. The expectorant eucalyptus limonene and standard myrtle oil enteric-coated capsules should not be taken with hot water.
In fact, unless there are specific special requirements in the drug instructions, it is best to take it with plain boiled water for oral medicine. It should be noted that, in addition to not being able to take the medicine with beverages, patients should avoid drinking fruit juice, milk and other beverages within half an hour before and after taking the medicine.
