What to do when you encounter hepatitis B during pregnancy

  Hepatitis B (hepatitis B for short) is mainly transmitted through blood, mother-to-child and sexual contact, and mother-to-child transmission is the main cause of chronic hepatitis B virus infection in infants. So, should pregnant women with hepatitis B be treated during pregnancy and how? How should a new born baby avoid hepatitis B?
  Pregnant women with hepatitis B should be treated during pregnancy. The
  2018 “Consensus on the Clinical Management of Women of Childbearing Age Infected with Hepatitis B Virus” pointed out that women infected with hepatitis B virus should be based on the level of glutamin transferase and hepatitis B virus gene load during pregnancy. Evaluate the severity of the disease, determine the purpose of treatment and management strategies. First of all, it is necessary to distinguish whether a pregnant woman is a carrier in the immune tolerance period or a patient with hepatitis B activity.
  Strategy of active hepatitis B treatment
  of hepatitis B in pregnant women with active during pregnancy can lead to liver failure, endangering the lives of pregnant women, especially pregnant women, pregnancy complications, such as intrahepatic cholestasis of pregnancy, pregnant women with fatty liver, diabetes, postpartum hemorrhage and puerperal infection The incidence is also high, especially pregnant women with advanced age and pregnancy complications are more dangerous, and may also have adverse effects on fetal development, such as low birth weight, fetal distress, premature birth, stillbirth, neonatal asphyxia and other hazards. Therefore, Pregnant women in the active period of hepatitis B should be actively treated. Timely antiviral treatment can not only quickly restore the liver function of pregnant women, complete the full-term pregnancy, but also reduce the risk of neonatal infection with hepatitis B virus.
  Treatment strategies of chronic hepatitis B carriers
  in pregnant women with chronic Hepatitis B carriers can relax is not it? Not at all. Although there is no hepatitis B activity, if hepatitis B E antigen (HBeAg) is positive and the hepatitis B virus gene load (HBV-DNA) is greater than 2×106 units/ml, the failure rate of neonatal combined immune blockade is higher. Therefore, antiviral treatment should also be carried out at 24 to 28 weeks of pregnancy, the main purpose is to reduce the risk of neonatal infection with hepatitis B virus by inhibiting hepatitis B virus replication. Due to concerns that immediate withdrawal of the drug after childbirth will lead to hepatitis B activity in pregnant women, it is generally recommended to stop the drug for 1 to 3 months after delivery.
  How to prevent newborns after delivery of pregnant women with hepatitis B
  An effective way to prevent perinatal transmission is through post-exposure prevention of newborns. Post-exposure prevention includes hepatitis B immune globulin and the initiation of recombinant hepatitis B vaccination at birth. This therapy has been proven to prevent the spread of hepatitis B virus in the perinatal period as high as 95%. Through passive immunization, hepatitis B immune globulin provides direct protection.
  Encountering hepatitis B during pregnancy is a challenge for pregnant women. However, as long as they are scientifically and effectively evaluated, prevented and treated under the guidance of doctors and pharmacists, they can ensure the safe passage of pregnancy, block mother-to-child transmission, and protect pregnant women. And the safety of the baby.