With the improvement of people’s quality of life, more and more people have increased uric acid, and the trend is becoming younger. Many people are troubled by increased uric acid, so what is the problem with increased uric acid?
First understand the ins and outs of uric acid in the body.
Uric acid is a catabolized product of a substance called purine in the body. There are two sources of it: one is the purine produced by the catabolism of human cells, which produces endogenous uric acid through the action of some enzymes, which accounts for about 80%. If the purine metabolism is disordered, it will lead to increased uric acid production; The second is that 20%-30% of uric acid comes from the diet, mainly because eating high purine foods, metabolic disorders occur, resulting in increased uric acid. In addition, drinking alcohol can also cause uric acid to increase, because ethanol will promote the accumulation of lactic acid in the body and inhibit the excretion of uric acid. During the fermentation of beer, a large amount of purine is produced and the blood uric acid is increased. Under normal circumstances, the daily production and excretion of uric acid are approximately equal. About two-thirds of the uric acid produced by metabolism is excreted by the kidneys. If the kidney function is damaged, causing excretion obstacles, it will increase the uric acid in the blood, and the remaining three-thirds One of the uric acid is excreted by the intestine. No matter which of the above-mentioned problems occurs, it will cause increased blood uric acid.
Increased blood uric acid harm to the body
Many people mention that increased uric acid will be associated with gout. In fact, otherwise, high uric acid will have different clinical manifestations at different stages.
Asymptomatic hyperuricemia: It can last 10-20 years, and some may not show symptoms for life. Unless it is tested, it is generally not easy to detect, but it cannot be taken by chance. Take it lightly. Symptoms are not obvious, and the onset is relatively subtle, making it difficult for patients to pay attention to, but being in a state of high uric acid for a long time will damage kidney function.
Gouty arthritis: When uric acid enters the joint tissues of the human body with the blood, and encounters local joint damage, overeating, excessive fatigue and other inducing factors, needle-like crystals are deposited in the joint synovial fluid and cause acute joint inflammation. The attack site is generally common in the thumb joint, ankle joint, knee joint, etc., and the attack is often accompanied by redness, swelling, heat, and severe pain. In the early stage of gout, these symptoms are more common in the lower extremities. And long-term gout patients can occur in the finger joints, as well as the cartilage tissue of the ear.
Gout nephropathy: uric acid crystals are deposited in the kidney, which can lead to acute and chronic uric acid nephropathy and urinary stones. Hematuria, proteinuria, and nocturia may increase. Long-term hyperuricemia gradually reduces kidney function, and eventually develops into renal insufficiency and renal failure.
How to prevent increased uric acid
First of all, we must pay attention to diet, it is best to light diet, eat more vegetables, but eat beans or eat as little as possible, avoid spinach. Eating more fruits, especially cherries, can lower uric acid. Eat less meat, seafood, animal offal, hot pots and other high-purine foods need to be strictly controlled.
Secondly, drink more boiled water or light tea, and drink less sweet drinks, and the daily urine output should be controlled at about 2000 ml. Beer is taboo, and other liquors must be strictly restricted.
In addition, we should pay attention to rest and exercise, work and rest, not stay up late, avoid overwork, relax and be optimistic. Proper aerobic exercise, soaking feet in hot water every day is also good.
Finally, if it has caused joint or kidney damage, it must be treated in a regular hospital in time.